Office of Research, UC Riverside
Sponsored Programs Administration



Cayuse 424 is a fast, easy-to-use Web application created specifically to simplify the creation, review, approval, and electronic submission of proposal applications.

For each opportunity posted on, Cayuse 424 downloads the appropriate forms into the Web application system, making it easy to select and apply for grants. Cayuse 424 supports over 98% of the opportunities posted on, allowing direct submission for grants posted by NIH, NSF, DOE, DOD, USDA, NASA, NOAA, EPA, DOE, SAMHSA, NEH, NEA, and many other federal agencies.

For more information regarding the use of Cayuse424 at UCR, please contact

Highlighted Benefits

  • Cayuse 424 delivers an advanced validation engine that cuts development time, eliminates rework and improves first-time submission success rates to near perfect.
  • During proposal development, the system performs real-time error checking based on agency and opportunity-specific rules, validations and other business rules. You can instantly zoom in on a specific error or warning, allowing you to resolve issues and submit error-free proposals.
  • Cayuse 424 users can view, edit, and collaborate on proposals in any stage of development.
  • Cayuse 424 maintains a complete repository and history of your proposals. You can quickly sort and filter proposals, copy them, transform them to different opportunities, and delete them.

Training Modules

How do I access Cayuse 424?

  • If you are a first time user of Cayuse 424, you will first need to establish a user account. Please contact Ms. Ursula Prins at, who will be able to link your UCR NetID to Cayuse to enable system access.
  • To access Cayuse 424, please click here and login using your UCR NetID and password.

Cayuse 424 Support Page and Resources: